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How Soluble GARP Enhances TGFβ Activation.

Sven Fridrich1, Susanne A Hahn2, Marion Linzmaier1

  • 1Cell and Matrix Biology, Institute of Zoology, JGU Mainz, Mainz, Germany.

Plos One
|April 8, 2016
PubMed
Summary

Glycoprotein A repetitions predominant (GARP) binds latent transforming growth factor-beta (TGFβ). Soluble GARP forms complexes with TGFβ, enhancing its immune-modulating activity.

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