Listeria Meningitis in an Immunocompetent Child
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Updated: Mar 23, 2026

Listeria monocytogenes Infection of the Brain
Published on: October 2, 2018
Giovanna Villa1, Maria Cristina Diana, Nicoletta Solari
1From the *Emergency Department of Paediatrics, Departments of †Clinical Pathology and Microbiology and ‡Hematology and Oncology, and §Infectious Diseases Unit, G. Gaslini Children's Hospital, Genoa, Italy.
Abstract:
Listeria monocytogenes is a facultative anerobic, gram-positive bacillus that is isolated from the soil, vegetables, and wild or domestic animals. Listeria infection is usually found in the older adults, immunocompromised patients, pregnant women, and newborns, whereas it is rare in healthy infants and children. Listeria monocytogenes may cause meningitis, meningoencephalitis, brain abscess, pyogenic arthritis, osteomyelitis, and liver abscess in children. The course of meningoencephalitis by Listeria is often severe and even fatal. Complications such as acute hydrocephalus, brain abscess, and spine abscess can develop, and the mortality associated with listeriosis is significantly high. We present a case of a previously healthy 7-year-old boy who developed Listeria monocytogenes meningitis.
Insights
Listeria monocytogenes meningitis is rare in healthy children but can be severe. This case highlights the potential for serious complications and high mortality in pediatric listeriosis.
Area of Science:
- Microbiology
- Infectious Diseases
- Pediatrics
Background:
- Listeria monocytogenes is a Gram-positive bacterium found in environmental sources.
- Listeriosis typically affects older adults, immunocompromised individuals, pregnant women, and newborns.
- Infection in healthy children is uncommon but can lead to severe neurological conditions.
Observation:
- A previously healthy 7-year-old boy presented with meningitis.
- The patient was diagnosed with Listeria monocytogenes meningitis.
Findings:
- Listeria monocytogenes can cause severe neurological infections in children, including meningitis, meningoencephalitis, and brain abscesses.
- Pediatric listeriosis can have a severe and potentially fatal course.
- Complications like hydrocephalus and spinal abscesses can arise, contributing to high mortality rates.
Implications:
- This case underscores the importance of considering Listeria monocytogenes in the differential diagnosis of meningitis in children, even those who are otherwise healthy.
- Prompt diagnosis and treatment are crucial to mitigate severe outcomes and reduce mortality associated with pediatric listeriosis.
- Further research into the pathogenesis and treatment of pediatric Listeria infections is warranted.
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