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Relationship between motor corticospinal excitability and ventilatory response during intense exercise
Takahiro Yunoki1, Ryouta Matsuura2, Ryo Yamanaka3
1Department of Human Development Sciences, Faculty of Education, Hokkaido University, Kita-11, Nishi-7, Kita-ku, Sapporo, 060-0811, Japan. yunoki@edu.hokudai.ac.jp.
European Journal of Applied Physiology
|April 9, 2016
Summary
Effort sense during intense exercise (IE) influences breathing. This study found that increased effort perception correlated with reduced corticospinal excitability in leg muscles, suggesting a link between effort and breathing control during strenuous activity.
Area of Science:
- Exercise Physiology
- Neuroscience
- Respiratory Control
Background:
- Effort sense is implicated in the hyperventilatory response during intense exercise (IE).
- The precise mechanism linking effort sense to increased ventilation during IE remains unclear.
- Understanding this link is crucial for elucidating respiratory control during high-intensity physical activity.
Purpose of the Study:
- To investigate the relationship between effort-mediated ventilatory response and corticospinal excitability in lower limb muscles during IE.
- To determine how changes in effort sense affect neuromuscular control during intense exercise.
- To elucidate the neural mechanisms underlying hyperventilation in response to perceived exertion.
Main Methods:
- Eight participants completed two bouts of intense cycling exercise (IE1st and IE2nd) at 75-85% of maximum workload.
- The second IE bout (IE2nd) followed a fatiguing submaximal exercise protocol to induce greater effort perception.
- Measurements included ventilatory response, effort sense of legs (ESL) using the Borg scale, and corticospinal excitability via motor evoked potentials (MEPs) in the vastus lateralis muscle.
Main Results:
- Ventilation's slope against CO2 output was significantly steeper during IE2nd compared to IE1st.
- Mean effort sense of legs (ESL) was significantly higher, and mean motor evoked potentials (MEPs) were significantly lower during IE2nd.
- The difference in ESL between the two bouts was significantly correlated with the difference in MEPs (p < 0.05, r = -0.82).
Conclusions:
- Effort-mediated hyperventilatory response during intense exercise may be associated with decreased corticospinal excitability of exercising muscles.
- Reduced corticospinal excitability could be a neural mechanism contributing to altered breathing patterns during prolonged or intense exercise.
- These findings highlight the complex interplay between sensory feedback, central motor command, and respiratory regulation during exercise.
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