Related Experiment Video
Updated: Mar 22, 2026

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
Published on: April 28, 2023
What Can We Learn from Interventions That Change Fat Distribution?
Pornpoj Pramyothin1, Kalypso Karastergiou2
1Division of Nutrition, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Asadang building, 8th floor, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.
Abstract:
Epidemiological studies have illustrated convincingly that fat distribution is associated with cardiometabolic risk. Fat deposition preferentially in the lower body, commonly seen in premenopausal women, is associated with lower risk, while central obesity in men and postmenopausal women is associated with higher risk. Studies of the physiology and the tissue and cellular characteristics of different adipose tissue depots, visceral and abdominal, gluteal, and femoral subcutaneous, corroborate this idea. In this report, we chose to focus on interventions-surgical, hormonal, lifestyle, and pharmacological-that directly or indirectly affect fat distribution, seeking further evidence for its pathophysiological significance.
Related Concept Videos
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution
Atherosclerosis III: Management
Cholesterol: Significance and Regulation
Considering cholesterol and...
Peripheral Artery Disease III: Interprofessional Care
Lipid-Lowering Drugs: Statins and Miscellaneous Agents
Drug Dosing: Obese Patients

