Related Experiment Video
Updated: Mar 22, 2026

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse
Published on: December 16, 2022
Early echocardiographic predictor of heart failure in cerebral arteriovenous malformations
Poonam P Thankavel1, Claudio Ramaciotti1
1Department of Pediatrics,Division of Cardiology,UT Southwestern Medical Center at Dallas and Children's Medical Center of Dallas,Dallas,Texas,United States of America.
Abstract:
Neonatal congestive heart failure in cerebral arteriovenous malformations carries a high risk of mortality. Severe heart failure leading to end-organ dysfunction may be a contraindication to early intervention. Although echocardiographic markers of haemodynamic instability exist, an objective echocardiographic predictor of severe heart failure is not available. We present a ratio of antegrade to retrograde flow in the aortic arch that objectively identifies those at the highest risk of mortality. This measurement can be easily obtained and has prognostic value at presentation, before clinical deterioration. Outcomes remain poor even when early intervention is offered, which may reflect irreversible neurological abnormalities.
Related Concept Videos
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests

