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Related Concept Videos

Dementia01:30

Dementia

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Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
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Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

2.0K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
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Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

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Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
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Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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Neural Regulation01:37

Neural Regulation

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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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[Neurosyphilis].

Brain and nerve = Shinkei kenkyu no shinpo·2026
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Related Experiment Video

Updated: Mar 22, 2026

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
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Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

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[Neurosyphilis and Dementia].

Hiroko Kato1, Tetsuo Ando

  • 1Department of Neurology, Anjo Kosei Hospital.

Brain and Nerve = Shinkei Kenkyu No Shinpo
|April 9, 2016
PubMed
Summary

Neurosyphilis, a form of syphilis affecting the brain, is increasing despite penicillin availability. Early diagnosis and treatment of general paresis can lead to complete recovery.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Public Health

Context:

  • Neurosyphilis incidence declined with penicillin but is now rising.
  • General paresis, a neurosyphilis form, mimics dementia and neurodegenerative diseases.
  • Accurate diagnosis is crucial for differentiating neurosyphilis from conditions like Alzheimer's disease.

Purpose:

  • To review the epidemiology, diagnosis, and treatment of neurosyphilis.
  • To highlight the importance of distinguishing general paresis from other dementia causes.
  • To present illustrative case studies of neurosyphilis.

Summary:

  • This study examines the resurgence of neurosyphilis, focusing on general paresis.
  • Key diagnostic criteria and effective treatment strategies are discussed.

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  • The potential for complete recovery with timely intervention is emphasized.

    • Impact:

    • Provides updated insights into neurosyphilis trends and management.
    • Aids clinicians in differentiating neurosyphilis from other neurological disorders.
    • Underscores the importance of recognizing and treating neurosyphilis for improved patient outcomes.