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Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
Published on: May 10, 2018
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[Dementia due to Endocrine Diseases].
Akiko Matsunaga1, Makoto Yoneda
1Department of Neurology, Faculty of Medical Sciences, University of Fukui Hospital.
Brain and Nerve = Shinkei Kenkyu No Shinpo
|April 9, 2016
Summary
Dementia can stem from endocrine diseases, unlike Alzheimer's disease, and is often treatable. Early diagnosis of endocrine-related dementia is crucial to prevent irreversible brain damage.
Area of Science:
- Endocrinology
- Neurology
- Internal Medicine
Context:
- Endocrine diseases affecting glands like the pituitary, thyroid, parathyroid, adrenals, and pancreas can manifest as dementia.
- Alzheimer's disease (AD) is a leading cause of dementia in the elderly, but it is currently untreatable.
Purpose:
- To highlight the treatable nature of endocrine-related dementia.
- To emphasize the diagnostic challenges due to overlapping symptoms with Alzheimer's disease.
- To underscore the importance of identifying and treating endocrine disorders to prevent irreversible cognitive decline.
Summary:
- Dementia caused by endocrine disorders is often treatable, contrasting with untreatable Alzheimer's disease.
- Patients may exhibit memory impairments similar to AD, alongside systemic and neuropsychiatric symptoms like involuntary movements, depression, or seizures.
- Differential diagnosis relies on identifying characteristic systemic symptoms and abnormalities in imaging and laboratory tests.
Impact:
- Facilitates accurate diagnosis and timely treatment of endocrine-related dementia.
- Prevents misdiagnosis of dementia, thereby avoiding delays in appropriate management.
- Aims to reduce the incidence of irreversible brain damage caused by untreated endocrine diseases.
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