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Updated: Mar 22, 2026

Techniques to Induce and Quantify Cellular Senescence
06:51

Techniques to Induce and Quantify Cellular Senescence

Published on: May 1, 2017

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Apoptotic transition of senescent cells accompanied with mitochondrial hyper-function.

Danli Wang1, Yang Liu1, Rui Zhang1

  • 1Center of Stem Cell and Regenerative Medicine, School of Medicine, Zhejiang University, Hangzhou, China.

Oncotarget
|April 9, 2016
PubMed
Summary

Cellular senescence involves cell-cycle arrest and metabolic shifts. This study shows that mitochondrial hyper-function in senescent cells drives their fate, potentially leading to apoptosis.

Keywords:
ROSapoptosismetabolismmitochondriasenescence

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