Related Experiment Video
Updated: Mar 22, 2026

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
Published on: September 27, 2024
Fractional CO2 Laser Versus Intense Pulsed Light in Treating Striae Distensae
Moustafa Adam El Taieb1, Ahmed Khair Ibrahim2
1Department of Dermatology, Venereology and Andrology, Qina Faculty of Medicine, South Valley University, Qena, Egypt.
Context:
Striae distensae are linear atrophic dermal scars covered with flat atrophic epidermis. They may cause disfigurement, especially in females. Many factors may cause striae distensae such as steroids, obesity, and pregnancy. Although there is no standard treatment for striae; many topical applications, peeling, and light and laser systems have been tried.
Aims:
To evaluate and compare the efficacy of fractional CO2 laser with intense pulse light in treating striae distensae.
Subjects And Methods:
Forty patients with striae distensae were recruited. Twenty of them were treated by fractional CO2 laser and 20 were treated with intense pulse light. Length and width of the largest striae were measured pre- and post-treatment. Patient satisfaction was also evaluated and graded. Patients were photographed after each treatment session and photos were examined by a blinded physician who had no knowledge about the cases.
Results:
Both groups showed significant improvement after treatments (P < 0.05). Patients treated with fractional CO2 laser showed significant improvement after the fifth session compared with those treated with ten sessions of intense pulsed light (P < 0.05) in all parameters except in the length of striae (P > 0.05).
Conclusions:
The current study has provided supportive evidence to the effectiveness of both fractional CO2 laser and intense pulse light as treatments for striae distensae. Fractional CO2 laser was found to be more effective in the treatment of striae distensae compared with intense pulse light.
Related Concept Videos
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care

