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Updated: Mar 22, 2026

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA
Published on: July 15, 2011
[Epidemiological analysis of leprosy in an endemic state of northeastern Brazil]
Karen Krystine Gonçalves de Brito1, Smalyanna Sgren da Costa Andrade1, Emanuele Malzac Freire de Santana1
1Universidade Federal da Paraíba, João Pessoa, Paraíba, Brasil.
Objective:
To characterise the trend of leprosy according to epidemiological and operational indicators in the state of Paraíba in the period of 2001-2011 with projections for the years 2012-2014.
Methods:
An epidemiological, retrospective, documentary study of a temporal sequence conducted with 10,476 reported cases of leprosy diagnosed in adults between 2001 and 2011 in 223 municipalities in the state of Paraiba, Brazil. The results were composed and analysed using two epidemiological indicators, an operational indicator and statistical software.
Results:
The annual detection rate of new cases showed an upward slope between 2001 and 2005 and a declining trend from 2006. Disability showed a cyclic variation with a downward tendency and a medium level of efficiency.
Conclusion:
The results show that the disease continues to be a problem in the state and reveal the need for shorter assessments that focus on health programmes and strategies that are used to fight leprosy.
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