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Seizures presenting as apnoea

Y Navelet1, C Wood, I Robieux

  • 1Service d'Explorations Fonctionnelles du Système Nerveux, Centre Hospitalier de Bicêtre, France.

Insights

A baby experienced recurrent cyanosis, apnoea, and bradycardia, initially misdiagnosed as oesophagitis. Further investigation revealed minor seizures, progressing to severe epilepsy with tonic-clonic seizures by 6 months old.

Area of Science:

  • Pediatric Neurology
  • Neonatal Medicine

Background:

  • Infantile episodes of cyanosis, apnoea, bradycardia, and abnormal limb movements can be challenging to diagnose.
  • Non-specific symptoms in infants require thorough investigation beyond initial findings.

Observation:

  • A 3-6 month old infant presented with recurrent, severe episodes of cyanosis, apnoea, bradycardia, and abnormal limb movements.
  • Initial investigations suggested oesophagitis, but symptoms persisted despite treatment.
  • Electroencephalography (EEG) and polygraphy later indicated the presence of minor seizures.

Findings:

  • The infant developed severe epilepsy with tonic-clonic seizures by 6 months of age.
  • The initial presentation mimicked other conditions, delaying definitive diagnosis.

Implications:

  • Highlights the importance of comprehensive diagnostic workups for recurrent infantile episodes.
  • Underscores the potential for neurological conditions to present with non-specific symptoms.
  • Emphasizes the need for advanced neurophysiological testing in persistent infant cases.

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