Related Experiment Video
Updated: Mar 22, 2026

Tissue Engineering of Tumor Stromal Microenvironment with Application to Cancer Cell Invasion
Published on: March 18, 2014
Florid pustular dermatitis of breast: A case report on a unusual complication from acellular dermal matrix use
Justin James1, Lee Jackson2, Christobel Saunders3
1Breast Surgery Unit, Fiona Stanley Hospital, 102-118 Murdoch Drive, Murdoch,WA 6150, Australia; Monash University, Faculty of Medicine, Nursing and Health Sciences, VIC 3800, Australia.
Introduction:
Idiopathic erythematous reaction of the breast (Red breast syndrome) is a known complication following breast reconstruction with acellular dermal matrix. However pustular dermatitis like presentation is not previously known.
Presentation Of Case:
We present a 42-year-old lady who developed bilateral pustular dermatitis like appearance following breast reconstruction with acellular dermal matrix slings. Though surgical washout was done, both expanders and flex HD could be preserved.
Discussion:
Acellular dermal matrix use is the only possible explanation for such a presentation and this can be considered a variant of red breast syndrome.
Conclusion:
Pustular dermatitis like presentation can be associated with acelluar dermal matrix use and should be considered in similar clinical presentations, since this can avoid unnecessary surgical procedures.
Related Concept Videos
The Extracellular Matrix
Papillary Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...

