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Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
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Inappropriate sinus tachycardia: focus on ivabradine

H S Abed1, J R Fulcher1, M J Kilborn1

  • 1Department of Cardiology, Royal Prince Alfred Hospital and NHMRC Clinical Trials Centre, University of Sydney, Sydney, New South Wales, Australia.

Internal Medicine Journal
|April 10, 2016
PubMed

Insights

Inappropriate sinus tachycardia (IST) causes high heart rate without a clear cause, impacting quality of life. Ivabradine shows promise in treating this condition when other therapies fail.

Area of Science:

  • Cardiology
  • Pharmacology

Background:

  • Inappropriate sinus tachycardia (IST) is a poorly understood condition causing elevated heart rate without a physiological stimulus.
  • IST significantly impacts patients' quality of life and lacks effective treatments.
  • Current treatments like beta-blockers are often ineffective or poorly tolerated.

Purpose of the Study:

  • To review the prevalence and mechanisms of inappropriate sinus tachycardia.
  • To examine the evidence for the efficacy of ivabradine in treating IST.

Main Methods:

  • Literature review of studies on inappropriate sinus tachycardia.
  • Analysis of clinical trial data and case reports on ivabradine for IST.

Main Results:

  • Ivabradine, a sinus node If funny current inhibitor, effectively reduces heart rate.
  • Emerging evidence suggests ivabradine is a promising treatment option for IST.

Conclusions:

  • Inappropriate sinus tachycardia requires further understanding of its mechanisms.
  • Ivabradine represents a potential new therapeutic avenue for managing IST.

Keywords:
inappropriate sinus tachycardiaivabradine

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