Does vitamin D deficiency trigger carpal tunnel syndrome?

Area of Science:

• Neurology
• Endocrinology
• Orthopedics

Background:

• Vitamin D deficiency is linked to various chronic diseases.
• Carpal tunnel syndrome (CTS) is a common condition affecting the hand and wrist.

Purpose of the Study:

• To investigate the relationship between serum vitamin D levels and carpal tunnel syndrome (CTS).
• To assess the correlation between vitamin D status, CTS severity, and pain levels.

Main Methods:

• Included 90 patients with mild to moderate CTS.
• Measured serum 25-hydroxyvitamin D levels.
• Evaluated pain using the Visual Analogue Scale and Douleur Neuropathique 4 Questionnaire (DN4).

Main Results:

• A significant difference in CTS severity was observed between vitamin D deficient and normal groups (p = 0.008).
• Positive correlations found between BMI and DN4 scores (r = 0.499, p = 0.025).
• Significant correlation between vitamin D levels and CTS severity in the deficiency group (r = 0.364, p = 0.004).

Conclusions:

• Vitamin D deficiency may be a potential trigger for CTS.
• CTS severity correlates with vitamin D levels in deficient individuals.
• Weight gain and neuropathic pain intensity are linked in CTS patients with vitamin D deficiency, suggesting routine vitamin D assessment.