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Updated: Mar 22, 2026

A Novel Rescue Technique for Difficult Intubation and Difficult Ventilation
Published on: January 17, 2011
Respiratory support for children in the emergency department
Andreas Schibler1, Donna Franklin1
1Paediatric Critical Care Research Group, Mater Research University Queensland, Lady Cilento Children's Hospital, Brisbane, Queensland, Australia.
Insights
Continuous positive airway pressure and high-flow nasal cannula therapy offer effective respiratory support for children in emergency settings. These methods provide oxygen and positive pressure, improving breathing and CO2 clearance, especially for conditions like asthma.
Area of Science:
- Pediatric Emergency Medicine
- Respiratory Care
Background:
- Respiratory support in pediatric emergencies spans from simple oxygen to mechanical ventilation.
- Emerging evidence suggests caution with oxygen due to potential reperfusion injuries.
- Non-invasive ventilation methods are increasingly utilized in emergency departments.
Purpose of the Study:
- To review current non-invasive respiratory support strategies for pediatric emergency settings.
- To highlight the benefits of continuous positive airway pressure and high-flow nasal cannula therapy.
- To identify indicators for successful treatment response.
Main Methods:
- Review of recent data and clinical practices in pediatric respiratory support.
- Analysis of the mechanisms and efficacy of continuous positive airway pressure (CPAP).
- Evaluation of high-flow nasal cannula (HFNC) therapy as an alternative support method.
Main Results:
- Continuous positive airway pressure is beneficial for mild to moderate respiratory distress.
- High-flow nasal cannula therapy provides positive pressure support, improves CO2 clearance, and reduces work of breathing.
- Decreased heart and respiratory rates early in HFNC therapy indicate treatment responders.
- CPAP is particularly effective for older children with asthma.
Conclusions:
- Early use of CPAP and HFNC therapy are valuable non-invasive options in pediatric emergency respiratory care.
- HFNC offers advantages in terms of equipment simplicity and child compliance.
- Monitoring physiological parameters can predict response to HFNC therapy.
Abstract:
Respiratory support in paediatric emergency settings ranges from oxygen delivery with subnasal oxygen to invasive mechanical ventilation. Recent data suggest that oxygen can cause reperfusion injuries and should be delivered with caution within well-defined clinical target ranges. Most mild to moderate respiratory distress conditions with an oxygen requirement may benefit from early use of continuous positive airway pressure. High-flow nasal cannula therapy (HFNC) is an emerging alternative way to support the inspiratory effort combined with oxygen delivery and positive expiratory pressures without the need of complicated equipment or good compliance from the child. Besides a positive pressure support effect, HFNC therapy reduces the physiological dead space with improved CO2 clearance. A decrease in heart and respiratory rate within the first few hours after initiation of HFNC therapy is likely to identify responders of the treatment. The use of non-invasive ventilation such as continuous positive airway pressure or the use of bi-level positive airway pressure ventilation in emergency departments has increased, and it has been recognised that continuous positive airway pressure support for older children with asthma is particularly efficient.
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