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Updated: Mar 22, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
In evidence-based medicine, more research is not always better…
Simon Dagenais1, O'Dane Brady2
1Spine Research LLC, 540 Main St #7, Winchester, MA 01890, USA.
Abstract:
Commentary On: Castro-Sánchez AM, Lara-Palomo IC, Matarán-Peñarrocha GA, Fernández-de-las-Peñas C, Saavedra-Hernández M, Cleland J, et al. Short-term effectiveness of spinal manipulative therapy versus functional technique in patients with chronic non-specific low back pain: a pragmatic randomized controlled trial. Spine J 2016:16:302-312 (in this issue).
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