Related Experiment Video
Updated: Mar 22, 2026
10:31
Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
Published on: May 2, 2025
804
Dermatoglyphics in kidney diseases: a review
Buddhika T B Wijerathne1, Robert J Meier2, Sujatha S Salgado3
1Department of Forensic Medicine, Faculty of Medicine and Allied Sciences, Rajarata University of Sri Lanka, Saliyapura, 50008 Sri Lanka.
Springerplus
|April 12, 2016
Summary
Dermatoglyphics, the study of fingerprint patterns, may help understand kidney disease origins. Limited studies suggest associations, but more research with larger sample sizes is needed to confirm findings.
Area of Science:
- Nephrology
- Genetics
- Dermatoglyphics
Background:
- Kidney diseases pose a significant global health burden.
- The etiology of some kidney diseases remains unclear.
- Dermatoglyphics, the study of epidermal ridge patterns, offers a potential non-invasive diagnostic tool for conditions with fetal origins.
Purpose of the Study:
- To systematically review and appraise existing literature on the association between dermatoglyphic variables and kidney diseases.
- To identify patterns and potential links between fingerprint characteristics and renal pathologies.
Main Methods:
- A systematic literature search was conducted across multiple databases (PubMed, POPLINE, Cochrane Library, Trip Database) and grey literature sources.
- Included studies were evaluated based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist.
- Fifteen relevant publications, including case reports, case series, and comparative studies, were analyzed.
Main Results:
- Limited studies suggest possible associations between dermatoglyphics and specific kidney diseases like Wilms tumor (fewer whorls, lower total ridge count) and adult polycystic kidney disease type III (lower mean total ridge count).
- Various case reports described dermatoglyphic findings in rare kidney-related syndromes.
- Whorl pattern frequency and total ridge count were frequently investigated variables.
Conclusions:
- Dermatoglyphics shows potential as a tool to investigate the etiology of certain kidney diseases.
- Current evidence is limited by small sample sizes and potential methodological issues.
- Further robust studies with adequate controls are necessary to establish definitive links and resolve etiological uncertainties.
Related Concept Videos
01:28Chronic Kidney Disease III: Interprofessional Care
595
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
595
01:20Renal Corpuscle
8.5K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
8.5K
01:25Chronic Kidney Disease I: Introduction
1.0K
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
1.0K
01:24Chronic Kidney Disease II: Clinical Manifestations
909
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
909
01:10Nephrons
8.4K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
8.4K
01:24Nephrotic Syndrome I : Introduction
885
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
885