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Published on: December 6, 2016
Gastroesophageal Reflux Affects Sleep Quality in Snoring Obese Children
Rodrigo Strehl Machado1, Frederick W Woodley2, Beth Skaggs3
1Department of Pediatrics, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.
Insights
Acidic gastroesophageal reflux (GER) disrupts sleep in obese children with snoring or restless sleep, even without obstructive sleep apnea (OSA). This study highlights GER as a key factor in poor sleep quality for this population.
Area of Science:
- Pediatric Sleep Medicine
- Gastroenterology
- Obesity Research
Background:
- Obese children often experience sleep disturbances.
- Snoring in obese children can indicate underlying sleep-disordered breathing.
- Gastroesophageal reflux (GER) is a potential contributor to sleep disruption.
Purpose of the Study:
- To assess sleep quality in obese children who snore but do not have obstructive sleep apnea (OSA).
- To investigate the relationship between sleep interruptions and GER in this specific pediatric group.
Main Methods:
- 13 snoring obese children underwent polysomnography with simultaneous multichannel intraluminal impedance and esophageal pH monitoring.
- Exclusion criteria included prior fundoplication, cystic fibrosis, and age under 2 years.
- Symptom-association probability analysis was used to link awakenings/arousals with reflux events.
Main Results:
- Sleep efficiency varied (median 81%).
- A significant number of awakenings (20.1%) were preceded by reflux episodes, predominantly acidic.
- In 38.5% of patients, awakenings were significantly associated with GER.
Conclusions:
- Acidic GER is a likely cause of sleep interruptions in obese children presenting with snoring or restless sleep.
- These findings are relevant for children without diagnosed obstructive sleep apnea (OSA).
- Identifying and managing GER may improve sleep quality in snoring obese children.
Purpose:
This study was performed to evaluate the quality of sleep in snoring obese children without obstructive sleep apnea (OSA); and to study the possible relationship between sleep interruption and gastroesophageal reflux (GER) in snoring obese children.
Methods:
Study subjects included 13 snoring obese children who were referred to our sleep lab for possible sleep-disordered breathing. Patients underwent multichannel intraluminal impedance and esophageal pH monitoring with simultaneous polysomnography. Exclusion criteria included history of fundoplication, cystic fibrosis, and infants under the age of 2 years. Significant association between arousals and awakenings with previous reflux were defined by symptom-association probability using 2-minute intervals.
Results:
Sleep efficiency ranged from 67-97% (median 81%). A total of 111 reflux episodes (90% acidic) were detected during sleep, but there were more episodes per hour during awake periods after sleep onset than during sleep (median 2.3 vs. 0.6, p=0.04). There were 279 total awakenings during the sleep study; 56 (20.1%) of them in 9 patients (69.2%) were preceded by reflux episodes (55 acid, 1 non-acid). In 5 patients (38.5%), awakenings were significantly associated with reflux.
Conclusion:
The data suggest that acid GER causes sleep interruptions in obese children who have symptoms of snoring or restless sleep and without evidence of OSA.
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