Related Experiment Video

Updated: Mar 22, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack

Published on: May 15, 2020

8.2K

[Consensus validation of a tool to identify inappropriate prescribing in pediatrics (POPI)]

S Prot-Labarthe1, T Weil2, N P K Nguyen2

  • 1Département de pharmacie, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Inserm ECEVE unité 1123, 75019 Paris, France; Groupe pédiatrie de la Société française de pharmacie clinique, France.

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|April 13, 2016
PubMed

Insights

A new screening tool, POPI, was developed to identify inappropriate prescriptions and drug omissions in pediatric care. This tool aims to reduce medication errors and improve patient safety in children.

Area of Science:

  • Pediatric Pharmacology
  • Drug Safety
  • Clinical Pharmacy

Background:

  • Medication errors, including inappropriate prescriptions and drug omissions, contribute to adverse drug events in children.
  • Effective screening tools are needed to enhance pediatric medication safety.

Purpose of the Study:

  • To develop a preliminary screening tool, POPI (Prescription and Omission Pediatric Indicator), for detecting inappropriate prescriptions and drug omissions in pediatric patients.
  • To base the tool's criteria on French and international guidelines for pediatric medication use.

Main Methods:

  • Criteria for the POPI tool were derived from disease prevalence and hospital statistics, informed by extensive French and international literature reviews.
  • The Delphi consensus technique, involving 16 French pediatric specialists (pharmacists and pediatricians), was employed to establish content validity.
  • A nine-point Likert scale was used to assess healthcare professionals' agreement and proposals for the criteria.

Main Results:

  • Criteria were organized by physiological systems: gastroenterology, respiratory infections, pain, neurology, dermatology, and miscellaneous.
  • Following two Delphi rounds, 101 out of 108 proposed criteria achieved strong consensus among panelists.
  • The consensus included 76 criteria for inappropriate prescriptions and 25 for drug omissions.

Conclusions:

  • POPI represents the first screening tool specifically designed to identify inappropriate prescriptions and omissions in pediatric medication management.
  • Further prospective studies are required to validate the inter-rater reliability and assess the detection capabilities of the POPI tool in clinical practice.
Abstract

More Related Videos

A Tablet-Based Curriculum-Based Measurement Protocol for Kindergarten Writing15:00

A Tablet-Based Curriculum-Based Measurement Protocol for Kindergarten Writing

Published on: February 7, 2025

1.2K
Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

52.6K

Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
368
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
713
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
1.4K
Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
1.9K
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
74
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
441