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Updated: Mar 22, 2026

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
Published on: July 26, 2024
The Quadriceps Vector is Most Parallel to the Spherical Axis With Minimal Difference for Gender or Ethnicity
Tomoharu Mochizuki1, J David Blaha2, Osamu Tanifuji3
1Department of Orthopedic Surgery, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan; Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan; Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, Michigan.
The spherical axis closely aligns with the quadriceps vector in total knee arthroplasty, regardless of gender or ethnicity. This finding suggests the spherical axis may guide kinematic alignment in knee replacement surgery.
Area of Science:
- Orthopedic surgery
- Biomechanics
- Medical imaging
Background:
- The extensor mechanism is crucial for kinematic alignment in total knee arthroplasty.
- Understanding the quadriceps vector's orientation is key for precise surgical alignment.
Purpose of the Study:
- To investigate gender and ethnic variations in quadriceps vector direction.
- To identify which established alignment axis best correlates with the quadriceps vector.
Main Methods:
- Computed tomography (CT) scans and patient data from 54 individuals (14 Caucasian, 40 Japanese) were analyzed.
- Three alignment axes (anatomic, mechanical, spherical) were measured against the quadriceps vector.
- Principal component analysis and 3D muscle modeling were used to determine the quadriceps vector.
Main Results:
- No statistically significant differences in quadriceps vector orientation were observed between genders or ethnicities.
- The quadriceps vector demonstrated the closest alignment with the spherical axis.
Conclusions:
- The spherical axis may serve as a universal guide for kinematic alignment in total knee arthroplasty.
- This axis, derived from motion, could enhance surgical precision in knee replacement procedures.
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