Association between BLK polymorphisms and susceptibility to SLE : A meta-analysis.

G G Song1, Y H Lee2

  • 1Division of Rheumatology, Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, 73, Inchon-ro, Seongbuk-gu, 136-705, Seoul, Korea.

Summary

This meta-analysis found that B-cell lymphocyte kinase (BLK) gene polymorphisms, specifically rs13277113 A/G, rs2736340 T/C, and rs2248932 T/C, are linked to increased susceptibility to systemic lupus erythematosus (SLE). These associations were significant across diverse ethnic groups, particularly in Caucasians and Asians.

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