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Angioleiomyoma in a conger (Conger conger)
1Dipartimento di Scienze Veterinarie, Polo Universitario dell'Annunziata, 98168 Messina, Italy.
Diseases of Aquatic Organisms
|April 13, 2016
Summary
This study identified an angioleiomyoma, a benign vascular tumor, in a European conger eel. This finding highlights the utility of immunohistochemistry in diagnosing fish neoplasms.
Area of Science:
- Veterinary Pathology
- Ichthyology
- Neoplastic Disease
Background:
- Neoplasms in fish require accurate diagnosis for effective management.
- Immunohistochemistry offers advanced diagnostic capabilities for fish tissues.
Observation:
- A wild adult male conger eel (Conger conger) presented with multiple ulcerous skin lesions.
- Histopathology revealed a sessile, ulcerated, hemorrhaging mass originating from the dermis.
Findings:
- The tumor consisted of spindle cells with vascular spaces, diagnosed as angioleiomyoma.
- Immunohistochemistry confirmed smooth muscle actin and CD34 positivity, with low MIB-1 proliferation index.
- Absence of infectious agents and glycogen storage ruled out other etiologies.
Implications:
- This is the first report of angioleiomyoma in fish using advanced immunohistochemical techniques.
- The study demonstrates the efficacy of monoclonal antibodies in fish neoplasm diagnosis.
- Establishes a valuable immunohistochemical approach for differentiating fish tumors.
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