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Updated: Mar 22, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
The golden era of biomedical informatics has begun
Jason H Moore1, John H Holmes1
1Department of Biostatistics and Epidemiology, Institute for Biomedical Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104-6116 USA.
Abstract:
Biomedical informatics has become a central focus for many academic medical centers and universities as biomedical research because increasingly reliant on the processing, analysis, and interpretation of large volumes of data, information, and knowledge. We posit here that this is the beginning of the golden era of biomedical informatics with opportunity for this maturing discipline to have a substantial impact on the biggest questions and challenges facing efforts to improve human health and the healthcare system.
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