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Related Experiment Videos

Contact dermatitis in children.

M Rademaker1, A Forsyth

  • 1Contact Dermatitis Investigation Unit, Belvidere Hospital, Glasgow, Scotland, UK.

Contact Dermatitis
|February 1, 1989
PubMed
Summary
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Metal, fragrance, and rubber allergies are common in children. Patch testing identified relevant allergens in 48% of pediatric patients, with significant reactions to metals and fragrances.

Area of Science:

  • Pediatric Dermatology
  • Allergology
  • Contact Dermatitis

Background:

  • Pediatric allergic contact dermatitis is a growing concern.
  • Identifying common allergens in children is crucial for effective management.

Purpose of the Study:

  • To investigate the prevalence and types of allergens causing positive reactions in children under 12 years.
  • To assess the relevance of positive patch test reactions.
  • To evaluate contact urticaria reactions to food additives and fragrances.

Main Methods:

  • Patch testing was performed on 125 children under 12 years over 7 years.
  • Reactions were assessed for relevance.
  • Contact urticaria testing included food additives and fragrances in a subset of children.

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Main Results:

  • 48% of children (60/125) showed at least one positive patch test reaction.
  • 92% of positive reactions were deemed relevant.
  • The most frequent allergens were metals (35), fragrances (24), and rubber compounds (11).
  • 20 out of 40 children tested for contact urticaria were positive, notably to benzoic acid (14) and cinnamaldehyde (12).

Conclusions:

  • Metals, fragrances, and rubber compounds are significant allergens in children.
  • Patch testing is effective in identifying relevant allergens in pediatric patients.
  • Contact urticaria to food additives and fragrances is also prevalent in this age group.