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Local anesthetic intolerance due to metabisulfite
A Dooms-Goossens1, A G de Alam, H Degreef
1Department of Medical Research (Dermatology), University Hospital, Katholieke Universiteit Leuven, Belgium.
Contact Dermatitis
|February 1, 1989
Abstract:
The case of a 40-year-old woman with severe edema of the face and neck after the injection of a local dental anesthetic is presented. The reaction is attributed to the presence of sodium metabisulfite, and antioxidant, in the local anesthetic. Both the anesthetic and the sodium metabisulfite gave a delayed positive patch-test response.