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Contrast Medium Induced Nephropathy after Endovascular Stent Graft Placement: An Examination of Its Prevalence and

Yohei Kawatani1, Yoshitsugu Nakamura1, Yoshihiko Mochida2

  • 1Department of Cardiovascular Surgery, Chiba-Nishi General Hospital, 107-1 Kanegasaku Matsudo-Shi, Chiba-Ken 2702251, Japan.

Radiology Research and Practice
|April 13, 2016
PubMed

Insights

Contrast-induced nephropathy (CIN) affects 7.8% of patients after endovascular stent graft repair for aortic aneurysms. Left ventricular dysfunction is a key risk factor for developing CIN.

Area of Science:

  • Cardiovascular Medicine
  • Nephrology
  • Interventional Radiology

Background:

  • Endovascular stent graft placement is a primary treatment for aortic aneurysms.
  • This minimally invasive procedure utilizes contrast media, posing a risk of contrast-induced nephropathy (CIN).
  • Understanding CIN incidence and risk factors is crucial for patient management.

Purpose of the Study:

  • To determine the incidence of CIN after endovascular stent graft placement for aortic aneurysm repair.
  • To identify significant risk factors associated with CIN development in this patient population.

Main Methods:

  • A retrospective study of 167 consecutive patients undergoing endovascular stent graft placement.
  • CIN diagnosis based on European Society of Urogenital Radiology criteria.
  • Statistical analyses included Chi-squared tests, t-tests, and multivariate logistic regression.

Main Results:

  • Thirteen patients (7.8%) developed CIN.
  • Left ventricular dysfunction and intraoperative blood transfusion were significantly more common in patients with CIN.
  • Multivariate analysis identified left ventricular dysfunction as the strongest predictor of CIN (OR 9.34, P=0.018).

Conclusions:

  • Left ventricular dysfunction is a significant risk factor for CIN in patients undergoing endovascular aortic aneurysm repair.
  • Patients with CIN experienced prolonged ICU and hospital stays.
  • Consideration of renal perfusion enhancement is recommended for high-risk patients, particularly those with left ventricular dysfunction.

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