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Advances in Mid-Infrared Spectroscopy for Chemical Analysis
Julian Haas1, Boris Mizaikoff1
1Institute of Analytical and Bioanalytical Chemistry, Ulm University, 89069 Ulm, Germany;
Annual Review of Analytical Chemistry (Palo Alto, Calif.)
|April 13, 2016
Summary
Mid-infrared (MIR) spectroscopy, utilizing advanced materials and techniques, now offers sensitive, high-resolution molecular analysis. This review highlights its evolution into a powerful tool for bioanalytics, medical diagnostics, and process analysis.
Area of Science:
- Spectroscopy
- Materials Science
- Analytical Chemistry
Background:
- Infrared spectroscopy has advanced significantly from a laboratory method.
- Progress in spectra acquisition and materials for generating, guiding, and detecting mid-infrared (MIR) radiation has been key.
- MIR spectroscopy now offers trace to ultratrace sensitivity and high spectral resolution.
Purpose of the Study:
- To review the evolution of MIR spectroscopy.
- To highlight advances in spectra acquisition and materials.
- To showcase innovative applications of MIR spectroscopy.
Main Methods:
- Review of recent progress in sophisticated spectra acquisition techniques.
- Analysis of advanced materials for MIR radiation generation, guidance, and detection.
- Examination of miniaturized device technology.
Main Results:
- MIR spectroscopy has become a state-of-the-art tool for sensing.
- It provides molecular information with high sensitivity and spectral resolution.
- Advances enable fast data acquisition rates.
Conclusions:
- MIR spectroscopy is a versatile technique with broad applications.
- Innovations have expanded its use in bioanalytics, biotechnology, and medical diagnostics.
- Miniaturization has been achieved without compromising analytical performance.
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