Related Experiment Video
Updated: Mar 22, 2026

Author Spotlight: Advancing Pediatric Epilepsy Surgery in Children Through Novel Biomarkers and Enhanced Localization
Published on: September 20, 2024
[Dysphoric disorders in epilepsy]
M C Usyukina1, S V Kornilova1, A S Shamanaev1
1Serbsky Federal Medical Research Centre of Psychiatry and Narcology, Moscow.
Objective:
to determine the differentiated clinical variants of dysphoric disorders in epilepsy based on their syndromal patterns, etiopathogenetic and dynamic characteristics.
Material And Methods:
Eighty men (mean age 32.7 years, illness duration from 11 to 20 years) were examined using clinical/psychopathological methods. Data analysis was performed with Statistika-10 software.
Results And Conclusion:
Dysphoric disorders in epilepsy were most frequent among affective disorders Paroxysmal, psychogenic and autochthonous dysphoric disorders were determined. Depending on the severity of one of the three axial affective components (anger, fear, melancholy): the explosive, phobic, depression, and moros-dysphoria were selected. According to the level of disorders, the dysphoric appearances were divided into simple, involving only affective symptoms, and complex, which contained, in addition to affective cerebroasthenic disorders, disorders of perception, thinking, consciousness, inclinations. Explosive psychogenic and paroxysmal dysphorias were most common. Psychogenic dysphoric reactions were most frequent in an isolated form in the clinical picture. Among combinations of dysphoric states, a combination of psychogenic and autochthonous dysphoric disorders occupied the leading place.
Related Concept Videos
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Antiepileptic Drugs: Potassium Channel Activators
Ezogabine has gained approval as an adjunctive treatment...
Antiepileptic Drugs: Calcium Channel Blockers
Calcium channel blockers exert their antiepileptic effects by targeting T-type calcium channels, which are integral to transmitting nerve signals in the central nervous system. These channels allow the passage of calcium ions, which are vital for neuronal communication. By inhibiting T-type calcium channels, calcium channel blockers effectively reduce the release of neurotransmitters and...
Electroconvulsive Therapy
Antiepileptic Drugs: Glutamate Antagonists

