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Concomitant Fundoplication With Gastrostomy: A Two-State Comparison Showing Continued Use of Reflux Medications
David Fox1, Elizabeth J Campagna, S Maria E Finnell
1*Department of Pediatrics, University of Colorado Denver, Denver †Adult and Child Consortium for Health Outcomes Research and Delivery Science, University of Colorado, Aurora, CO ‡Children's Health Services Research, Department of Pediatrics, Indiana University School of Medicine, Indianapolis, IN §Department of Surgery, University of Colorado Denver, Denver, CO.
Insights
Fundoplication rates varied between Colorado and North Carolina in children undergoing gastrostomy, despite similar patient characteristics. Antireflux surgery did not reduce reflux medication use post-procedure.
Area of Science:
- Pediatric surgery
- Gastroenterology
- Health services research
Background:
- Fundoplication is a surgical procedure to treat gastroesophageal reflux.
- Practice patterns for pediatric surgical procedures can vary geographically.
- The association between fundoplication and medication use for reflux requires further investigation.
Purpose of the Study:
- To compare fundoplication practice differences between Colorado and North Carolina in pediatric gastrostomy patients.
- To analyze reflux medication use patterns in relation to concomitant fundoplication.
Main Methods:
- Retrospective observational cohort study of Medicaid-insured children (2006-2008) in Colorado and North Carolina.
- Included children who received a surgical gastrostomy.
- Analyzed concomitant fundoplication rates and 30-day prescription fills for reflux medications pre- and post-gastrostomy.
Main Results:
- A total of 969 pediatric gastrostomy admissions were analyzed (CO: 341, NC: 628).
- Concomitant fundoplication rates differed significantly (CO: 60%, NC: 43%; P < 0.01).
- Fundoplication was not associated with a reduction in reflux medication use post-discharge in either state.
Conclusions:
- Significant geographic variation exists in fundoplication rates for pediatric gastrostomy patients.
- Antireflux surgery (fundoplication) did not demonstrate a reduction in the need for reflux medications.
- Further research is needed to understand the drivers of practice variation and optimize reflux management.
Objectives:
We sought to determine whether practice differences for fundoplication exist between 2 geographically distinct states, and to determine the reflux medication use pattern associated with concomitant fundoplication.
Methods:
A retrospective observational cohort study of children in Colorado (CO) and North Carolina (NC) insured by Medicaid from 2006 to 2008. Children who received a surgical gastrostomy during the study period were included, and our primary outcome measure was the performance of a concomitant gastric fundoplication. Thirty-day prescription fills for reflux medications were examined before and after gastrostomy procedure.
Results:
We examined 969 surgical gastrostomy admission in both states over the 3-year study period (CO, n = 341 and NC, n = 628). Patients in each state had similar age (median age, 6 months, P = 0.97). Use of pH probe (CO: 15%, NC: 11%) and diagnosis of reflux (CO: 84%, NC: 72%) differed in each state. Concomitant fundoplication was performed in 60% of patients in CO and 43% in NC (P < 0.01). Age less than 6 months was associated with an increased adjusted odds of fundoplication in CO (OR 9.77, CI, 3.91, 24.43), but less so in NC (OR 2.73, CI, 1.48, 5.04). Among patients undergoing gastrostomy, the proportion of patients on reflux medication 4 to 6 months post-discharge did not differ between those receiving fundoplication and those that did not in either state.
Conclusions:
Rates of concomitant fundoplication varied in the 2 states despite patients having similar demographic and clinical characteristics. Antireflux surgery was not associated with a reduction in reflux medications in either state.
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