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Outcome of preterm infants born to overweight and obese mothers†

S Danieli-Gruber1, A Maayan-Metzger1,2, I Schushan-Eisen1,2

  • 1a Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel , and.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|April 14, 2016
PubMed

Insights

Preterm infants born to overweight or obese mothers face higher maternal risks but show similar neonatal outcomes compared to those born to normal-weight mothers. This suggests that maternal BMI does not significantly impact infant health post-birth.

Area of Science:

  • Obstetrics and Gynecology
  • Neonatology
  • Public Health

Background:

  • Maternal overweight and obesity are significant global health concerns.
  • These conditions are associated with increased risks of obstetric complications.
  • The impact on preterm neonates requires further investigation.

Purpose of the Study:

  • To compare perinatal morbidity and mortality in preterm neonates born to overweight/obese mothers versus normal-weight mothers.
  • To identify specific neonatal outcomes affected by maternal pre-pregnancy body mass index (BMI).

Main Methods:

  • Retrospective chart review of 110 preterm infants (gestational age 28-34 weeks) born to overweight/obese mothers and 110 matched controls.
  • Data collected included maternal pre-pregnancy BMI, and maternal/neonatal complications.
  • Infants were born between 2007 and 2014 at Sheba Medical Center.

Main Results:

  • Obese mothers had higher rates of pregnancy-induced hypertension and cesarean deliveries.
  • Overweight mothers showed increased incidence of gestational diabetes.
  • No significant differences were observed in neonatal outcomes including Apgar scores, respiratory distress, cardiac issues, brain pathologies, infections, or hospitalization duration.

Conclusions:

  • Despite increased maternal complications, preterm infants born to overweight and obese mothers do not appear to be at a higher risk for neonatal complications.
  • This finding highlights the importance of maternal health management during pregnancy for preterm infant outcomes.
Abstract

Keywords:
Maternal obesityneonatal outcomepreterm infants

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