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Quantification of Cerebral Vascular Architecture using Two-photon Microscopy in a Mouse Model of HIV-induced Neuroinflammation
Published on: January 12, 2016
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Multiple Intracranial Aneurysms in HIV Infection
Sumeet R Dhawan1, Anju Gupta1, Vivek Gupta2
1Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
Indian Journal of Pediatrics
|April 14, 2016
Summary
Neurological complications in HIV patients are frequent, but intracranial aneurysms are rare. This case highlights an unusual presentation of an aneurysmal bleed in a child with HIV.
Area of Science:
- Neurology
- Infectious Diseases
- Pediatrics
Background:
- Neurological manifestations are common in individuals with human immunodeficiency virus (HIV).
- These often include cognitive impairment, microcephaly, white matter lesions, and seizures.
- Cerebral vasculopathy and stroke are less common complications.
Observation:
- A 7-year-old boy presented with a severe headache.
- Diagnostic evaluation revealed an intracranial aneurysm.
Findings:
- The patient experienced an aneurysmal bleed, a rare neurological complication in HIV.
- The underlying cause of the aneurysm in this pediatric HIV case requires further investigation.
Implications:
- This case underscores the importance of considering uncommon neurological complications in HIV patients.
- Early diagnosis and management of intracranial aneurysms are crucial for favorable outcomes.
- Further research is needed to understand the specific mechanisms linking HIV and intracranial aneurysms in children.
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