Related Experiment Video
Updated: Mar 22, 2026
06:30
Assessment of Static Graviceptive Perception in the Roll-Plane using the Subjective Visual Vertical Paradigm
Published on: April 28, 2020
6.3K
Subjective Visual Vertical in PD Patients with Lateral Trunk Flexion
F Gandor1, D Basta2, D Gruber1
1Movement Disorders Clinic, Strasse nach Fichtenwalde 16, 14547 Beelitz-Heilstätten, Germany.
Parkinson'S Disease
|April 14, 2016
Summary
Parkinson's disease (PD) patients with lateral trunk flexion (LTF) show significant deviations in their subjective visual vertical (SVV), suggesting vestibular dysfunction contributes to this common PD symptom.
Area of Science:
- Neurology
- Vestibular System Research
- Movement Disorders
Background:
- Lateral trunk flexion (LTF) is a frequent characteristic in Parkinson's disease (PD).
- Emerging evidence links LTF in PD to peripheral vestibular system impairments.
- Subjective visual vertical (SVV) deviation is a known indicator of vestibular processing disorders.
Purpose of the Study:
- To investigate the relationship between vestibular dysfunction and LTF in Parkinson's disease.
- To determine if SVV deviation is associated with the presence and severity of LTF in PD patients.
Main Methods:
- Assessed SVV angles in 30 Parkinson's disease patients using a bedside test.
- Compared SVV angles between PD patients with and without LTF.
- Categorized LTF as reversible or fixed.
Main Results:
- PD patients exhibiting LTF had significantly larger SVV angles compared to those without LTF (p < 0.001).
- Pathological SVV was observed in 14 out of 21 patients with LTF, versus none of the 9 patients without LTF.
- Abnormal SVV was more prevalent in cases of reversible LTF.
Conclusions:
- Pathological SVV in PD patients with LTF indicates vestibular dysbalance.
- Vestibular dysfunction may play a role in the pathophysiology of LTF in Parkinson's disease.
Related Concept Videos
01:15Parkinson's Disease: Overview
2.3K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
2.3K
01:24Parkinson's Disease: Treatment
1.3K
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
1.3K