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Surgical Treatment for Infective Endocarditis: A Single-Centre Experience
Sossio Perrotta1, Anders Jeppsson1, Victoria Fröjd2
1Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.
The Thoracic and Cardiovascular Surgeon
|April 14, 2016
Summary
Surgery for infective endocarditis has high early mortality and complication rates, but acceptable long-term survival. Outcomes for native and prosthetic valve endocarditis were similar in this study.
Area of Science:
- Cardiovascular Surgery
- Infectious Diseases
Background:
- Infective endocarditis frequently necessitates surgical intervention.
- This study evaluates short- and medium-term surgical outcomes for infective endocarditis.
- Outcomes were compared between native and prosthetic valve endocarditis.
Purpose of the Study:
- To assess the results of surgical treatment for infective endocarditis.
- To compare outcomes between native and prosthetic valve endocarditis.
Main Methods:
- Retrospective study of 254 operations for infective endocarditis (Jan 2008 - May 2015).
- Included 182 native valve and 72 prosthetic valve endocarditis cases.
- Data collected on patient characteristics, operative details, complications, and mortality.
Main Results:
- Early mortality (30-day) was 8.7% (7.7% native, 11.1% prosthetic), not statistically significant.
- Severe perioperative complications occurred in 39% of operations.
- 1- and 5-year survival rates were 86% and 75%, respectively, with no significant difference between native and prosthetic valves.
- 8% of patients experienced recurrent endocarditis requiring surgery.
Conclusions:
- Surgical treatment for infective endocarditis remains associated with significant early mortality and morbidity.
- Long-term outcomes are generally acceptable.
- No significant differences in morbidity or mortality were observed between native and prosthetic endocarditis in this cohort.
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