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Causes of donor rejection in a sperm banking program.
M Schroeder-Jenkins1, S A Rothmann
1Department of Laboratory Hematology, Cleveland Clinic Foundation, Ohio 44195-5020.
Fertility and Sterility
|May 1, 1989
Summary
A three-stage screening protocol efficiently identified qualified sperm donors, with 32% of applicants becoming active donors. Sperm cryopreservation, however, led to a 27% increase in donor rejection.
Area of Science:
- Reproductive Medicine
- Andrology
- Sperm Banking
Background:
- Sperm donation programs require rigorous donor screening to ensure semen quality and safety.
- Efficient and cost-effective screening protocols are crucial for the sustainability of sperm banks.
Purpose of the Study:
- To evaluate the efficacy of a three-stage screening protocol for selecting sperm donors.
- To assess the impact of sperm cryopreservation on donor acceptance rates.
Main Methods:
- A 2-year prospective study screened 93 male applicants (ages 18-46) using a three-stage protocol.
- Semen specimens underwent cryopreservation, quarantine, and release for insemination.
Main Results:
- Thirty (32%) applicants qualified as active sperm donors.
- Eighty-five percent of semen specimens were successfully processed and released.
- Sperm cryopreservation resulted in a 27% increase in the rejection of otherwise acceptable donors.
Conclusions:
- The three-stage protocol is an efficient, cost-effective method for selecting qualified sperm donors.
- Sperm cryopreservation significantly impacts donor acceptance rates, necessitating careful consideration in screening protocols.