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Risk factors of diabetic foot Charcot arthropathy: a case-control study at a Malaysian tertiary care centre
Aishah Ahmad Fauzi1, Tze Yang Chung1, Lydia Abdul Latif1
1Department of Rehabilitation Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Insights
A history of prior diabetic foot problems significantly increases the risk of developing diabetic Charcot arthropathy. Early preventive management is crucial for diabetic patients, especially those with chronic conditions.
Area of Science:
- Podiatry
- Diabetology
- Epidemiology
Background:
- Diabetic Charcot arthropathy is a serious complication of diabetes mellitus.
- Identifying risk factors is essential for effective prevention and management strategies.
Purpose of the Study:
- To determine the risk factors associated with diabetic Charcot arthropathy of the foot.
- To compare risk factors in diabetic patients with and without foot problems.
Main Methods:
- A case-control study was conducted involving diabetic patients at a specialized clinic in Malaysia.
- Data collected included sociodemographic profiles, foot-related factors, and diabetes characteristics.
Main Results:
- A history of previous foot problems (ulcer, amputation, surgery) was the strongest predictor (OR 26.4) of developing Charcot arthropathy.
- Other significant risk factors included younger age (<60 years), long diabetes duration (>10 years), and diabetic nephropathy.
- Unilateral Charcot foot, predominantly midfoot, was observed in 83.3% of affected patients.
Conclusions:
- Prior diabetic foot problems represent the most significant risk factor for Charcot arthropathy.
- Preventive foot care in primary settings and multidisciplinary approaches are vital for managing chronic diabetic patients.
Introduction:
This study aimed to determine the risk factors of diabetic Charcot arthropathy of the foot among diabetic patients with and without foot problems.
Methods:
This was a case-control study involving diabetic patients attending the Diabetic Foot Care and Wound Management Clinic at University Malaya Medical Centre, Kuala Lumpur, Malaysia, from June 2010 to June 2011. Data on sociodemographic profiles, foot factors and diabetes characteristics was collected and analysed.
Results:
A total of 48 diabetic patients with Charcot arthropathy of the foot were identified. Data from these 48 patients was compared with those of 52 diabetic patients without foot problems. Up to 83.3% of patients with diabetic Charcot arthropathy presented with unilateral Charcot foot, most commonly located at the midfoot (45.8%). Patients with a history of foot problems, including foot ulcer, amputation, surgery or a combination of problems, had the highest (26-time) likelihood of developing Charcot arthropathy (odds ratio 26.4; 95% confidence interval 6.4-109.6). Other significant risk factors included age below 60 years, more than ten years' duration of diabetes mellitus and the presence of nephropathy.
Conclusion:
A history of prior diabetic foot problems is the greatest risk factor for developing diabetic Charcot arthropathy, compared with other risk factors such as diabetes characteristics and sociodemographic profiles. Preventive management of diabetic foot problems in the primary care setting and multidisciplinary care are of paramount importance, especially among chronic diabetic patients.
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