Methods to Evaluate the Preclinical Safety and Immunogenicity of Genetically Modified Live-Attenuated Leishmania

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Sreenivas Gannavaram1, Parna Bhattacharya2, Ranadhir Dey2

  • 1Laboratory of Emerging Pathogens, Division of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA. Sreenivas.gannavaram@fda.hhs.gov.

Methods in Molecular Biology (Clifton, N.J.)
|April 15, 2016
PubMed

Keywords:
BiomarkersImmune suppressionImmunogenicityInnate immunityNon-pathogenicityPersistenceProtective antigensSafety

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