[Malignant primary bone tumors. Diagnosis, therapy and results of treatment]

Differences in the biological behavior of primary bone tumors have led to the development of differentiated treatment regimes. In recent years, a considerable improvement in the results of treatment has been accomplished, in particular by the introduction of adjuvant chemotherapy. The various therapeutic concepts for the three most common malignant bone tumors, osteosarcoma, chondrosarcoma and Ewing's sarcoma are described and, on the basis of the author's own results, discussed.