Related Experiment Video
Updated: Mar 22, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
Published on: October 11, 2018
Flexible variable selection for recovering sparsity in nonadditive nonparametric models
Zaili Fang1, Inyoung Kim1, Patrick Schaumont2
1Department of Statistics, Virginia Tech., Blacksburg, Virginia, U.S.A.
Abstract:
Variable selection for recovering sparsity in nonadditive and nonparametric models with high-dimensional variables has been challenging. This problem becomes even more difficult due to complications in modeling unknown interaction terms among high-dimensional variables. There is currently no variable selection method to overcome these limitations. Hence, in this article we propose a variable selection approach that is developed by connecting a kernel machine with the nonparametric regression model. The advantages of our approach are that it can: (i) recover the sparsity; (ii) automatically model unknown and complicated interactions; (iii) connect with several existing approaches including linear nonnegative garrote and multiple kernel learning; and (iv) provide flexibility for both additive and nonadditive nonparametric models. Our approach can be viewed as a nonlinear version of a nonnegative garrote method. We model the smoothing function by a Least Squares Kernel Machine (LSKM) and construct the nonnegative garrote objective function as the function of the sparse scale parameters of kernel machine to recover sparsity of input variables whose relevances to the response are measured by the scale parameters. We also provide the asymptotic properties of our approach. We show that sparsistency is satisfied with consistent initial kernel function coefficients under certain conditions. An efficient coordinate descent/backfitting algorithm is developed. A resampling procedure for our variable selection methodology is also proposed to improve the power.
More Related Videos
13:54A Workflow for Lipid Nanoparticle LNP Formulation Optimization using Designed Mixture-Process Experiments and Self-Validated Ensemble Models SVEM
Published on: August 18, 2023
07:34A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions
Published on: March 25, 2014
Related Concept Videos
Quantifying and Rejecting Outliers: The Grubbs Test
Statistical Inference Techniques in Hypothesis Testing: Parametric Versus Nonparametric Data
Parametric statistics, as the name suggests, assumes that data follow a specific distribution, often a normal distribution. This assumption enables robust hypothesis testing and estimation. Parametric methods, like the Student's t-test or Goodness-of-fit test, are frequently employed in biostatistics due to their robustness. For instance,...
Clearance Models: Noncompartmental Models
The noncompartmental approach capitalizes on extensive sampling data, correlating the volume of distribution to systemic exposure and the administered dosage. This method enables...
Introduction to Nonparametric Statistics
One of...
Parametric Survival Analysis: Weibull and Exponential Methods
Weibull Distribution
The Weibull distribution is a flexible model used in parametric survival analysis. It can handle both increasing and decreasing hazard rates, depending on its shape parameter...
Variability: Analysis
The range is a simple measure of variability, indicating the difference between the highest and...