Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Assessment of Diffusion and Perfusion

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...

Applications Of NMR In Biology

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.

Two-Dimensional (2D) NMR: Overview

Two-Dimensional (2D) NMR: Overview

The 1D NMR spectrum of large and complex molecules like natural products has complicated splitting patterns and overlapping signals, which can be easily interpreted using 2-dimensional (2D) NMR. Unlike 1D NMR, 2D NMR has two frequency axes that provide the coupling information between the nucleus A and nucleus B in a molecule. The process from which 2D spectra are obtained has four steps.
The first step is the preparation period, during which nucleus A is excited with a radiofrequency pulse....

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

No significant differences in ultrasound morphology after endovenous laser ablation with 1940-nm versus 1470-nm radially emitting fibers: A one-year prospective randomized multicenter study.

Phlebology·2026

Same author

Chronic Injuries to the Distal Biceps and Triceps Tendons: Current Evidence, Treatment Strategies, and Clinical Implications.

Zeitschrift fur Orthopadie und Unfallchirurgie·2026

Same author

Multispectral 7 Tesla MRI as a potential predictor of dopamine transporter deficiency in Parkinson's disease.

Imaging neuroscience (Cambridge, Mass.)·2026

Same author

Effectiveness and Limitations of Endovenous Laser Ablation for Anterior Saphenous Vein Insufficiency: A Single-Center Retrospective Study.

Journal of clinical medicine·2026

Same author

Influence of co-registration on lesion characterization in diffusion-weighted breast MRI.

Magma (New York, N.Y.)·2026

Same author

Overestimation of the Apparent Diffusion Coefficient in Diffusion-Weighted Imaging Due to Residual Fat Signal and Out-of-Phase Conditions.

Tomography (Ann Arbor, Mich.)·2026

Same journal

Erratum: Low-dimensional model for adaptive networks of spiking neurons [Phys. Rev. E 111, 014422 (2025)].

Physical review. E·2026

Same journal

Disentangling the effects of many-body forces on depletion interactions.

Physical review. E·2026

Same journal

Charge transport and mode transition in dual-energy electron beam diodes.

Physical review. E·2026

Same journal

Optimization of multisite reactions in complex compartmentalized media.

Physical review. E·2026

Same journal

Origin of geometric cohesion in nonconvex granular materials: Interplay between interdigitation and rotational constraints enhancing frictional stability.

Physical review. E·2026

Same journal

Interaction of walkers with a standing Faraday wave.

Physical review. E·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 22, 2026

Diffusion Imaging in the Rat Cervical Spinal Cord

Diffusion Imaging in the Rat Cervical Spinal Cord

Published on: April 7, 2015

NMR-based diffusion lattice imaging.

Frederik Bernd Laun¹, Lars Müller¹, Tristan Anselm Kuder¹

¹Medical Physics in Radiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.

Physical Review. E

|April 15, 2016

Summary

This summary is machine-generated.

Nuclear magnetic resonance (NMR) diffusion experiments can fully map connected porous systems. The SERPENT sequence reveals detailed structure information in open, well-connected materials.

More Related Videos

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Related Experiment Videos

Last Updated: Mar 22, 2026

Diffusion Imaging in the Rat Cervical Spinal Cord

Diffusion Imaging in the Rat Cervical Spinal Cord

Published on: April 7, 2015

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Area of Science:

Physics
Materials Science
Chemistry

Background:

Nuclear magnetic resonance (NMR) diffusion experiments are valuable for studying structures that impede diffusion, such as cell membranes.
Previous studies demonstrated NMR's utility in determining the averaged shape of closed pores.
The extent of structural information obtainable from open, well-connected systems using NMR diffusion experiments remains an open question.

Purpose of the Study:

To theoretically investigate the information content of NMR diffusion experiments in open, well-connected periodic systems.
To demonstrate that full structural information can be accessed in such systems.

Main Methods:

Utilizing the "SEquential Rephasing by Pulsed field-gradient Encoding N Time intervals" (SERPENT) sequence.
Employing multiple diffusion encoding gradient pulses with varying amplitudes.
Analyzing two-dimensional solid matrices (hexagonal cylinder lattice, rectangular isosceles triangle lattice) within an NMR-visible medium.

Main Results:

The study demonstrates that the full structural information of connected periodic systems is accessible through NMR diffusion experiments.
The SERPENT sequence effectively probes the complex geometry of open porous structures.
Specific lattice structures (hexagonal cylinders, rectangular triangles) were analyzed to validate the method.

Conclusions:

NMR diffusion experiments, particularly with advanced sequences like SERPENT, can provide comprehensive structural insights into open, well-connected porous materials.
This theoretical work expands the applicability of NMR diffusion techniques beyond closed pore systems.
The findings pave the way for more detailed characterization of complex materials using NMR.