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Author Spotlight: Rabies-Specific Antibody Isotypes Detection in Sera or Cerebral Spinal Fluid Using an IFA Test
Published on: January 19, 2024
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Rabies direct fluorescent antibody test does not inactivate rabies or eastern equine encephalitis viruses
Jodie A Jarvis1, Mary A Franke2, April D Davis1
1Rabies Laboratory, Wadsworth Center, New York State Department of Health, Slingerlands, NY, USA.
Journal of Virological Methods
|April 16, 2016
Abstract:
An examination using the routine rabies direct fluorescent antibody test was performed on rabies or Eastern equine encephalitis positive mammalian brain tissue to assess inactivation of the virus. Neither virus was inactivated with acetone fixation nor the routine test, thus laboratory employees should treat all samples as rabies and when appropriate Eastern equine encephalitis positive throughout the whole procedure.
Keywords:
AcetoneDiagnosisDirect fluorescent antibody testEastern equine encephalitisInactivationRabies
