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Updated: Mar 22, 2026

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons
Published on: August 23, 2016
[Zika virus infection during pregnancy]
O Picone1, C Vauloup-Fellous2, E D'Ortenzio3
1Department of obstetrics and gynecology, hôpital Foch, 40, rue Worth, 92151 Suresnes, France; EA2493, UFR des sciences de la santé Simone-Veil, université Versailles Saint-Quentin-en-Yvelines, 78180 Montigny-le-Bretonneux, France.
The Zika virus epidemic poses risks to pregnant women, potentially causing severe neurodevelopmental issues in newborns. This review examines current recommendations for managing Zika virus infection during pregnancy.
Area of Science:
- Virology
- Neuroscience
- Maternal-Fetal Medicine
Background:
- Ongoing Zika virus epidemic in the Americas.
- Zika virus linked to congenital infections and neurodevelopmental dysfunction.
- Uncertainty regarding fetal infection incidence and other complications.
Purpose of the Study:
- Review current recommendations for managing pregnancy with suspected or confirmed Zika virus infection.
- Provide guidance for healthcare professionals and public health authorities.
- Address knowledge gaps on fetal Zika virus complications.
Main Methods:
- Literature review of existing Zika virus research and public health guidelines.
- Synthesis of current epidemiological data and clinical observations.
- Analysis of recommended diagnostic and management strategies.
Main Results:
- Zika virus infection in pregnant women is a significant public health concern.
- Potential for severe neurodevelopmental outcomes in affected infants.
- Mandatory declaration of Zika virus infection in France highlights its importance.
Conclusions:
- Current recommendations emphasize caution and prevention measures for pregnant women.
- Further research is needed to fully understand fetal complications.
- Standardized management protocols are crucial for pregnant women exposed to Zika virus.
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