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Updated: Mar 22, 2026

Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique
Published on: September 7, 2022
The dura causes spinal cord compression after spinal cord injury
Samira Saadoun1, Melissa C Werndle1, Luis Lopez de Heredia2
1a Academic Neurosurgery Unit , St George's University of London , London , UK ;
Abstract:
MR scans from 65 patients with traumatic spinal cord injury were analysed; on admission 95% had evidence of cord compression - in 26% due to the dura, and in the remaining 74% due to extradural factors. Compression due to dural factors resolved with a half-life of 8.7 days. These findings suggest that bony decompression alone may not relieve spinal cord compression in the quarter of patients in whom dural factors are significant.
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