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Hypercalciuria in children with diabetes mellitus
Helvetica Paediatrica Acta
|February 1, 1989
Summary
Diabetic children may face kidney damage risk from high urinary calcium. About a quarter of these children exhibit hypercalciuria, a condition of excessive calcium in urine, without signs of kidney disease.
Area of Science:
- Pediatric Endocrinology
- Nephrology
- Metabolic Disorders
Background:
- Diabetic children are susceptible to various complications.
- Hypercalciuria is a potential risk factor for renal damage.
Purpose of the Study:
- To investigate the prevalence of hypercalciuria in diabetic children without nephropathy.
- To explore potential correlations between urinary calcium excretion and glycemic control.
Main Methods:
- Assessed urinary calcium excretion in 75 diabetic children without nephropathy.
- Analyzed diurnal variation and correlations with glucose excretion and HbA1c levels.
Main Results:
- 17 out of 75 (approximately 23%) diabetic children showed urinary calcium excretion exceeding 4 mg/kg/day.
- No significant diurnal variation in calciuria was observed.
- No correlation was found between calcium excretion and glucose excretion or HbA1c levels.
Conclusions:
- A notable proportion of diabetic children without nephropathy exhibit hypercalciuria.
- These children may be at increased risk for renal damage due to elevated calcium excretion.
- Further monitoring of urinary calcium is recommended for diabetic children.