Related Experiment Video
Updated: Mar 22, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
Published on: December 8, 2014
Approach to a Child with Colitis
Sirish K Palle1,2, Mahadev Prasad1, Subra Kugathasan3,4,5
1Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
This review covers pediatric colitis, focusing on inflammatory bowel disease (IBD) and its rising incidence in developing nations. It highlights genetic, environmental, and dietary factors influencing IBD
Area of Science:
- Pediatric Gastroenterology
- Inflammatory Bowel Disease (IBD) Research
Background:
- Colitis in children presents diverse etiologies, including infectious, inflammatory, and allergic causes.
- Inflammatory bowel disease (IBD) is an increasingly significant cause of chronic colitis in pediatric populations.
- Epidemiologic shifts indicate rising IBD incidence in developing countries and among immigrant populations.
Purpose of the Study:
- To review the etiology, pathogenesis, and clinical features of pediatric colitis.
- To detail the diagnostic and management strategies for pediatric inflammatory bowel disease (IBD).
- To explore the changing epidemiology and contributing factors of IBD in specific global regions.
Main Methods:
- Comprehensive literature review of pediatric colitis and inflammatory bowel disease (IBD).
- Analysis of recent epidemiologic reports on IBD incidence and prevalence.
- Synthesis of current research on genetic, environmental, and dietary influences on IBD.
Main Results:
- Pediatric colitis diagnosis and management are influenced by onset, age, and geography.
- Inflammatory bowel disease (IBD) is a growing concern, particularly in South-East Asia/India and among South-Asian immigrants.
- Research is actively investigating the drivers behind increased IBD rates in developing nations and immigrant groups.
Conclusions:
- Understanding the varied causes of pediatric colitis is crucial for effective management.
- The increasing global burden of pediatric inflammatory bowel disease (IBD) necessitates further research into its complex etiology.
- Identifying genetic, environmental, and dietary factors is key to addressing the rising incidence of IBD.
Related Concept Videos
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease IV: Pharmacological Management
Pharmacologic...

