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Related Concept Videos

Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Gonorrhoea diagnostics: An update.

R Verma, S Sood1

  • 1Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.

Indian Journal of Medical Microbiology
|April 16, 2016
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Summary
This summary is machine-generated.

Diagnosing gonorrhoea remains difficult, with current tests having limitations. New, affordable point-of-care tests are needed for accurate diagnosis and to combat the spread of this sexually transmitted infection.

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Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Gonorrhoea diagnosis is challenging due to the fastidious nature of Neisseria gonorrhoeae.
  • Asymptomatic infections are common, leading to undetected transmission and complications.
  • Conventional methods and current nucleic acid amplification tests (NAATs) have limitations, including cost and accuracy.

Purpose of the Study:

  • To highlight the diagnostic challenges of gonorrhoea.
  • To discuss the limitations of existing diagnostic methods for Neisseria gonorrhoeae.
  • To emphasize the need for improved, cost-effective diagnostic technologies.

Main Methods:

  • Review of current diagnostic approaches for gonorrhoea.
  • Analysis of limitations of bacterial culture and NAATs.
  • Discussion of the impact of syndromic management on diagnostic practices.

Main Results:

  • Bacterial culture for Neisseria gonorrhoeae is declining, leading to loss of skills.
  • NAATs offer improved sensitivity but suffer from sequence-related issues and cannot assess antibiotic susceptibility.
  • Current methods are unaffordable in resource-limited settings.

Conclusions:

  • There is a critical need to revive gonococcal culture skills and adopt new technologies.
  • Innovation is required for accurate, cost-effective gonorrhoea diagnosis.
  • Development of a point-of-care test for this bacterial sexually transmitted infection is essential.