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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
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The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
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Related Experiment Video

Updated: Mar 22, 2026

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
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Ambras syndrome: A rare case report.

A Ishita1, G P Sujatha, G V Pramod

  • 1Department of Oral Medicine and Radiology, Bapuji Dental College and Hospital, Davangere, Karnataka, India.

Journal of the Indian Society of Pedodontics and Preventive Dentistry
|April 16, 2016
PubMed
Summary

This case report details a rare instance of Ambras syndrome (AS), a condition involving congenital generalized hypertrichosis and gingival hyperplasia. The study highlights a 4-year-old boy with these rare symptoms and distinct facial features.

Area of Science:

  • Genetics and rare diseases
  • Dermatology and oral medicine

Background:

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  • Congenital generalized hypertrichosis and gingival hyperplasia are rare conditions, with hypertrichosis incidence reported as one in billions.
  • These conditions, when occurring together, are termed Ambras syndrome (AS) and are typically present at birth or shortly after.
  • Ambras syndrome is characterized by excessive hair growth and gingival fibromatosis, often accompanied by dysmorphic facial features.