Multimodality Imaging in Coronary Artery Disease: Focus on Computed Tomography

Ji Hyun Lee1, Donghee Han1, Ibrahim Danad1

  • 1Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital and Weill Cornell Medical College, New York, NY, USA.

Insights

Computed tomography (CT) offers advanced, noninvasive methods for assessing coronary artery disease (CAD), the top global cause of death. This review details CT

Area of Science:

  • Cardiovascular imaging
  • Radiology
  • Medical diagnostics

Background:

  • Coronary artery disease (CAD) is a major global health concern, driving mortality worldwide.
  • Traditional diagnostic methods for CAD exist, but advancements are crucial.
  • Computed tomography (CT) technology has significantly improved cardiac imaging capabilities.

Purpose of the Study:

  • To review the role of CT in assessing coronary artery disease (CAD).
  • To explore various CT-based imaging modalities for CAD evaluation.
  • To discuss the implications, benefits, limitations, and future of these CT techniques.

Main Methods:

  • Review of current literature on cardiac CT imaging for CAD.
  • Focus on specific CT modalities: coronary artery calcium screening, coronary CT angiography, myocardial CT perfusion, and fractional flow reserve CT.
  • Analysis of clinical applications, advantages, and disadvantages of each method.

Main Results:

  • Cardiac CT provides accurate and noninvasive evaluation of CAD.
  • Specific CT techniques offer detailed insights into coronary artery calcification, anatomy, and myocardial blood flow.
  • Fractional flow reserve CT (FFR-CT) shows promise in functional assessment.

Conclusions:

  • CT-based imaging is a valuable tool for diagnosing and assessing the severity of CAD.
  • Each modality offers unique benefits and has specific limitations.
  • Continued technological advancements in CT will likely expand its role in cardiovascular care.

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