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Updated: Mar 22, 2026

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
Published on: December 7, 2012
Recent Advances in Preventing Adverse Reactions to Transfusion
Thomas S Rogers1, Mark K Fung1, Sarah K Harm1
1Blood Bank & Transfusion Medicine, University of Vermont Medical Center, Burlington, Vermont, 05401, USA; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Burlington, Vermont, 05401, USA.
Abstract:
The spectrum of adverse reactions to blood product transfusion ranges from a benign clinical course to serious morbidity and mortality. There have been many advances in technologies and transfusion strategies to decrease the risk of adverse reactions. Our aim is to address a few of the advancements in increasing the safety of the blood supply, specifically pathogen reduction technologies, bacterial contamination risk reduction, and transfusion associated acute lung injury risk mitigation strategies.
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