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Related Experiment Videos

An Ulcerated Plaque in a Gay Man.

H Lui, W A McLeod, W S Wood

    Archives of Dermatology
    |April 16, 2016
    PubMed
    Summary
    This summary is machine-generated.

    A case report details a 28-year-old man with HIV presenting a forehead nodule. Diagnosis involved a skin biopsy and India ink staining for this rare presentation.

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    Area of Science:

    • Dermatology
    • Infectious Diseases
    • Pathology

    Background:

    • A 28-year-old homosexual man with a history of HIV infection presented with a persistent forehead nodule.
    • The lesion clinically mimicked basal cell carcinoma but had an unusual presentation.

    Purpose of the Study:

    • To present a diagnostic challenge in a patient with multiple risk factors for opportunistic infections.
    • To illustrate the diagnostic approach for an unusual cutaneous lesion in an immunocompromised individual.

    Main Methods:

    • Clinical examination of a solitary, ulcerated forehead nodule.
    • Review of patient's medical history including HIV, inflammatory bowel disease, and intravenous drug abuse.
    • Microscopic examination of a "touch" preparation from a skin biopsy, stained with India ink.

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    Main Results:

    • The nodule was a 2.0 × 1.5-cm ulcerated lesion on the forehead.
    • Patient history included HIV, inflammatory bowel disease, anal condyloma, and previous Pneumocystis carinii pneumonia.
    • India ink staining of the biopsy specimen was performed for diagnostic purposes.

    Conclusions:

    • The case highlights the importance of considering opportunistic infections in the differential diagnosis of cutaneous lesions in HIV-positive individuals.
    • Diagnostic methods like India ink staining are crucial for identifying specific pathogens in immunocompromised patients.