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A High-Quality Biobank Supports Breast Cancer Research in Harbin, China
Guangwen Zhang1, Bingshu Xia2,3, Tong Liu2
11 Breast Cancer Biobank, Harbin Medical University Cancer Hospital, Harbin, China .
Insights
A breast cancer biobank was established in 2009, collecting over 100,000 high-quality biospecimens. This resource supports translational research and the development of targeted breast cancer therapies.
Area of Science:
- Oncology
- Biobanking
- Translational Medicine
Background:
- Established a standard breast cancer biobank at Harbin Medical University Cancer Hospital (HMUCH) in 2009.
- Collected over 100,000 biospecimens, including human breast cancer samples, matched blood, and adjacent normal tissues.
- Deposited specimens from patients and healthy donors into the repository.
Purpose of the Study:
- To report the establishment and crucial role of the HMUCH biobank in translational medicine research.
- To summarize the biobank's utilization and influence on research projects since its inception.
- To highlight the biobank's contribution to verifying biomarkers for targeted breast cancer therapies.
Main Methods:
- Collected and stored high-quality human breast cancer samples, matched blood samples, and adjacent normal tissues.
- Processed and distributed biological specimens adhering to international standard operating procedures.
- Annotated tissue samples for research use.
Main Results:
- Successfully established and operated a biobank with over 100,000 biospecimens.
- Demonstrated the biobank's significant utilization and influence on numerous research projects.
- Provided high-quality, well-annotated samples crucial for biomarker discovery.
Conclusions:
- The HMUCH biobank is a vital resource for translational breast cancer research.
- The biobank facilitates the identification of specific biomarkers for targeted therapy development.
- High-quality, well-annotated biospecimens are essential for advancing breast cancer treatment strategies.
Abstract:
We established a standard breast cancer biobank at Harbin Medical University Cancer Hospital (HMUCH) in 2009. More than 100,000 biospecimens, including high-quality human breast cancer samples, matched blood samples, and adjacent normal tissues, were collected from patients and healthy donors in HMUCH and were then deposited in the repository. We reported the establishment of a biobank in our hospital and its crucial role in translational medicine research. We stored, processed, and distributed qualified biological specimens in accordance with international standard operating procedures. We also summarized the utilization of this biobank and its influence on research projects over the years since its establishment. Therefore, we can verify specific biomarkers that may aid in the development of targeted breast cancer therapies by using high-quality, well-annotated tissue samples provided by the biobank.
